Electronic Health Records (EHRs) often lack explicit links between medications and diagnoses, making clinical decision-making and research more difficult. Even when links exist, diagnosis lists may be incomplete, especially during early patient visits. Discharge summaries tend to provide more complete information, which can help infer accurate diagnoses, especially with the help of large language models (LLMs). This study investigates whether LLMs can predict implicitly mentioned diagnoses from clinical notes and link them to corresponding medications. We address two research questions: (1) Does majority voting across diverse LLM configurations outperform the best single configuration in diagnosis prediction? (2) How sensitive is majority voting accuracy to LLM hyperparameters such as temperature, top-p, and summary length? To evaluate, we created a new dataset of 240 expert-annotated medication-diagnosis pairs from 20 MIMIC-IV notes. Using GPT-3.5 Turbo, we ran 18 prompting configurations across short and long summary lengths, generating 8568 test cases. Results show that majority voting achieved 75 percent accuracy, outperforming the best single configuration at 66 percent. No single hyperparameter setting dominated, but combining deterministic, balanced, and exploratory strategies improved performance. Shorter summaries generally led to higher accuracy.In conclusion, ensemble-style majority voting with diverse LLM configurations improves diagnosis prediction in EHRs and offers a promising method to link medications and diagnoses in clinical texts.

Smart manufacturing systems increasingly rely on adaptive control mechanisms to optimize complex processes. This research presents a novel approach integrating Soft Actor-Critic (SAC) reinforcement learning with digital twin technology to enable real-time process control in robotic additive manufacturing. We demonstrate our methodology using a Viper X300s robot arm, implementing two distinct control scenarios: static target acquisition and dynamic trajectory following. The system architecture combines Unity's simulation environment with ROS2 for seamless digital twin synchronization, while leveraging transfer learning to efficiently adapt trained models across tasks. Our hierarchical reward structure addresses common reinforcement learning challenges including local minima avoidance, convergence acceleration, and training stability. Experimental results show rapid policy convergence and robust task execution in both simulated and physical environments, with performance metrics including cumulative reward, value prediction accuracy, policy loss, and discrete entropy coefficient demonstrating the effectiveness of our approach. This work advances the integration of reinforcement learning with digital twins for industrial robotics applications, providing a framework for enhanced adaptive real-time control for smart additive manufacturing process.

Systematic literature review is essential for evidence-based medicine, requiring comprehensive analysis of clinical trial publications. However, the application of artificial intelligence (AI) models for medical literature mining has been limited by insufficient training and evaluation across broad therapeutic areas and diverse tasks. Here, we present LEADS, an AI foundation model for study search, screening, and data extraction from medical literature. The model is trained on 633,759 instruction data points in LEADSInstruct, curated from 21,335 systematic reviews, 453,625 clinical trial publications, and 27,015 clinical trial registries. We showed that LEADS demonstrates consistent improvements over four cutting-edge generic large language models (LLMs) on six tasks. Furthermore, LEADS enhances expert workflows by providing supportive references following expert requests, streamlining processes while maintaining high-quality results. A study with 16 clinicians and medical researchers from 14 different institutions revealed that experts collaborating with LEADS achieved a recall of 0.81 compared to 0.77 experts working alone in study selection, with a time savings of 22.6%. In data extraction tasks, experts using LEADS achieved an accuracy of 0.85 versus 0.80 without using LEADS, alongside a 26.9% time savings. These findings highlight the potential of specialized medical literature foundation models to outperform generic models, delivering significant quality and efficiency benefits when integrated into expert workflows for medical literature mining.

Innate values describe agents' intrinsic motivations, which reflect their inherent interests and preferences to pursue goals and drive them to develop diverse skills satisfying their various needs. The essence of reinforcement learning (RL) is learning from interaction based on reward-driven behaviors, much like natural agents. It is an excellent model to describe the innate-values-driven (IV) behaviors of AI agents. Especially developing the awareness of the AI agent through balancing internal and external utilities based on its needs in different tasks is a crucial problem for individuals learning to support AI agents integrating human society with safety and harmony in the long term. This paper proposes a hierarchical compound intrinsic value reinforcement learning model -- innate-values-driven reinforcement learning termed IVRL to describe the complex behaviors of AI agents' interaction. We formulated the IVRL model and proposed two IVRL models: DQN and A2C. By comparing them with benchmark algorithms such as DQN, DDQN, A2C, and PPO in the Role-Playing Game (RPG) reinforcement learning test platform VIZDoom, we demonstrated that rationally organizing various individual needs can effectively achieve better performance.

Automatic scene generation is an essential area of research with applications in robotics, recreation, visual representation, training and simulation, education, and more. This survey provides a comprehensive review of the current state-of-the-arts in automatic scene generation, focusing on techniques that leverage machine learning, deep learning, embedded systems, and natural language processing (NLP). We categorize the models into four main types: Variational Autoencoders (VAEs), Generative Adversarial Networks (GANs), Transformers, and Diffusion Models. Each category is explored in detail, discussing various sub-models and their contributions to the field. We also review the most commonly used datasets, such as COCO-Stuff, Visual Genome, and MS-COCO, which are critical for training and evaluating these models. Methodologies for scene generation are examined, including image-to-3D conversion, text-to-3D generation, UI/layout design, graph-based methods, and interactive scene generation. Evaluation metrics such as Frechet Inception Distance (FID), Kullback-Leibler (KL) Divergence, Inception Score (IS), Intersection over Union (IoU), and Mean Average Precision (mAP) are discussed in the context of their use in assessing model performance. The survey identifies key challenges and limitations in the field, such as maintaining realism, handling complex scenes with multiple objects, and ensuring consistency in object relationships and spatial arrangements. By summarizing recent advances and pinpointing areas for improvement, this survey aims to provide a valuable resource for researchers and practitioners working on automatic scene generation.

Objectives: Our objective is to create an end-to-end system called AutoRD, which automates extracting information from clinical text about rare diseases. We have conducted various tests to evaluate the performance of AutoRD and highlighted its strengths and limitations in this paper. Materials and Methods: Our system, AutoRD, is a software pipeline involving data preprocessing, entity extraction, relation extraction, entity calibration, and knowledge graph construction. We implement this using large language models and medical knowledge graphs developed from open-source medical ontologies. We quantitatively evaluate our system on entity extraction, relation extraction, and the performance of knowledge graph construction. Results: AutoRD achieves an overall F1 score of 47.3%, a 14.4% improvement compared to the base LLM. In detail, AutoRD achieves an overall entity extraction F1 score of 56.1% (rare_disease: 83.5%, disease: 35.8%, symptom_and_sign: 46.1%, anaphor: 67.5%) and an overall relation extraction F1 score of 38.6% (produces: 34.7%, increases_risk_of: 12.4%, is_a: 37.4%, is_acronym: 44.1%, is_synonym: 16.3%, anaphora: 57.5%). Our qualitative experiment also demonstrates that the performance in constructing the knowledge graph is commendable. Discussion: AutoRD demonstrates the potential of LLM applications in rare disease detection. This improvement is attributed to several design, including the integration of ontologies-enhanced LLMs. Conclusion: AutoRD is an automated end-to-end system for extracting rare disease information from text to build knowledge graphs. It uses ontologies-enhanced LLMs for a robust medical knowledge base. The superior performance of AutoRD is validated by experimental evaluations, demonstrating the potential of LLMs in healthcare.

Innate values describe agents' intrinsic motivations, which reflect their inherent interests and preferences to pursue goals and drive them to develop diverse skills satisfying their various needs. The essence of reinforcement learning (RL) is learning from interaction based on reward-driven (such as utilities) behaviors, much like natural agents. It is an excellent model to describe the innate-values-driven (IV) behaviors of AI agents. Especially in multi-agent systems (MAS), building the awareness of AI agents to balance the group utilities and system costs and satisfy group members' needs in their cooperation is a crucial problem for individuals learning to support their community and integrate human society in the long term. This paper proposes a hierarchical compound intrinsic value reinforcement learning model -- innate-values-driven reinforcement learning termed IVRL to describe the complex behaviors of multi-agent interaction in their cooperation. We implement the IVRL architecture in the StarCraft Multi-Agent Challenge (SMAC) environment and compare the cooperative performance within three characteristics of innate value agents (Coward, Neutral, and Reckless) through three benchmark multi-agent RL algorithms: QMIX, IQL, and QTRAN. The results demonstrate that by organizing individual various needs rationally, the group can achieve better performance with lower costs effectively.

In recent years, edge computing has served as a paradigm that enables many future technologies like AI, Robotics, IoT, and high-speed wireless sensor networks (like 5G) by connecting cloud computing facilities and services to the end users. Especially in medical and healthcare applications, it provides remote patient monitoring and increases voluminous multimedia. From the robotics angle, robot-assisted therapy (RAT) is an active-assistive robotic technology in rehabilitation robotics, attracting many researchers to study and benefit people with disability like autism spectrum disorder (ASD) children. However, the main challenge of RAT is that the model capable of detecting the affective states of ASD people exists and can recall individual preferences. Moreover, involving expert diagnosis and recommendations to guide robots in updating the therapy approach to adapt to different statuses and scenarios is a crucial part of the ASD therapy process. This paper proposes the architecture of edge cognitive computing by combining human experts and assisted robots collaborating in the same framework to help ASD patients with long-term support. By integrating the real-time computing and analysis of a new cognitive robotic model for ASD therapy, the proposed architecture can achieve a seamless remote diagnosis, round-the-clock symptom monitoring, emergency warning, therapy alteration, and advanced assistance.

Adopting reasonable strategies is challenging but crucial for an intelligent agent with limited resources working in hazardous, unstructured, and dynamic environments to improve the system's utility, decrease the overall cost, and increase mission success probability. This paper proposes a novel directed acyclic strategy graph decomposition approach based on Bayesian chaining to separate an intricate policy into several simple sub-policies and organize their relationships as Bayesian strategy networks (BSN). We integrate this approach into the state-of-the-art DRL method -- soft actor-critic (SAC), and build the corresponding Bayesian soft actor-critic (BSAC) model by organizing several sub-policies as a joint policy. We compare our method against the state-of-the-art deep reinforcement learning algorithms on the standard continuous control benchmarks in the OpenAI Gym environment. The results demonstrate that the promising potential of the BSAC method significantly improves training efficiency.

As a unifying concept in economics, game theory, and operations research, even in the Robotics and AI field, the utility is used to evaluate the level of individual needs, preferences, and interests. Especially for decision-making and learning in multi-agent/robot systems (MAS/MRS), a suitable utility model can guide agents in choosing reasonable strategies to achieve their current needs and learning to cooperate and organize their behaviors, optimizing the system's utility, building stable and reliable relationships, and guaranteeing each group member's sustainable development, similar to the human society. Although these systems' complex, large-scale, and long-term behaviors are strongly determined by the fundamental characteristics of the underlying relationships, there has been less discussion on the theoretical aspects of mechanisms and the fields of applications in Robotics and AI. This paper introduces a utility-orient needs paradigm to describe and evaluate inter and outer relationships among agents' interactions. Then, we survey existing literature in relevant fields to support it and propose several promising research directions along with some open problems deemed necessary for further investigations.